Yunzhi has been used in traditional Chinese medicine for centuries to strengthen the body’s immune system and fight against various severe diseases. Increasingly more scientific research and clinical trials have proven that Yunzhi extract helps stimulate the immune system so that the body is better able to defend against the serious illness. Yunzhi is an effective complementary treatment option for people with serious illness at various stages.
The main effects of Yunzhi (Coriolus Versicolor) published in the following research reports include:
- Activation of immune cells such as: T-lymphocytes, B-lymphocytes, monocytes, macrophages, bone marrow cells, natural killer cells and lymphokine-activated cells1,2,3.
- Increase of antibodies and a variety of cytokines such as: interleukin-2, interleukin-6, interferon and TNF2,4.
- Restore immunological response depression derived from serious illness treatment back to normal level2,3.
- Enhance the body’s immunity5,6to reduce chance of infection2,4.
- Reduce the side effects of the treatment of serious illnesses, improve patient’s mental and health status7.
- Inhibit mutated cells proliferation5,8.
- Increase the survival rate of patients5,9,10,11.
1) Chu K.K.W., Chow A.H.L. (2006) Preparation and standardization of immunomodulatory pepdite-linked glucans with verifiable oral absorbability from coriolus versicolor. United States patent filling: US 7,048,932 B2
2) Chu K.K.W., Ho S.S.S., Chow A.H.L. (2002) Coriolus versicolor: a medical mushroom with promising immunotherapeutic values. J Clin Pharmacol, 42(9):976-84 (Link1, Link2)
3) Liu F., Ooi V.E.C, Fung M.C. (1999) Analysis of immunomodulating cytokines mRNAs in the mouse induced by mushroom polysaccharides. Life Sci. 64(12):1005-11
4) Tsukagoshi S., Hashimoto Y., Fugii G., Kabayashi H., Namoto K., Orita K. (1984) Krestin (PSK). Cancer Treatment Rev. 11:131-55
5) King-Fai Cheng, Ping-Chung Leung (2008) General review of polysaccharopeptides (PSP) from c.versicolor: pharmacological and clinical studies. Cancer Therapy Vol.6:117-30
6) Leung M.Y. K., Liu C., Koon J.C.M., Fung K.P. (2006) Polysaccharide biological response modifiers. Immunology Letters 105:104-14
7) Zhong Y., Zou J., Zhang L.Y. (2001) Clinical observation on alleviating chemotherapy’s side effect of PSP in treating gastric carcinoma. Liaoning Journal of Traditional Chinese Medicine 28:668-9
8) Zhou Y.L., Hua J., Lin J., Tang K.X. (2007) Cytotoxic activities of coriolous versicolor (Yunzhi) extracts on human liver cancer and breast cancer cell line. Afr J. Biotechnol 6:1740-43
9) Mohammad H. Saleh1,2†, Iran Rashedi2 and Armand Keating1,2* Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide
